Using previously genotyped controls in genome-wide association studies (GWAS): application to the Stroke Genetics Network (SiGN)

Genome-wide association studies (GWAS) are widely applied to identify susceptibility loci for a variety of diseases using genotyping arrays that interrogate known polymorphisms throughout the genome.A particular strength of GWAS is that it is unbiased with respect to specific genomic elements (e.g., coding read more or regulatory regions of genes),

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Cherubism with idiopathic gingival enlargement: A rare case report

Cherubism is a congenital childhood disease of autosomal dominant inheritance.It is a benign, familial giant cell lesion characterized by gradually progressive painless swelling of the jaws.Idiopathic gingival enlargement is a rare condition and may be associated with some uncommon syndromes.This case report describes an 11-year-old patient with un

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